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The Kunming Institute of Zoology, Chinese Academy of Sciences, and the Fourth School of the Chinese Academy of Sciences Decipher the world's first poison frog base

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Today (January 24th), the reporter learned from the Kunming Institute of Zoology, Chinese Academy of Sciences that the Institute, together with researchers from the University of North Carolina at Charlotte, the University of California and the University of Pittsburgh, successfully deciphered the world's first poison frog genome – Strawberry Arrow Poison frog genome.

The Kunming Institute of Zoology, Chinese Academy of Sciences, and the Fourth School of the Chinese Academy of Sciences Decipher the world's first poison frog base -The-Kunming-Institute-of-Zoology-Chinese-Academy-of-Sciences-and-the-Fourth-School-of-the-Chinese-Academy-of-Sciences-Decipher-the-world39s-first-poison-frog-base

The poison dart frog is a small land frog that lives in lowland forests along the Caribbean coast of Central and South America. Its strong toxicity, colorful colors and unique living habits make the poison dart frog unusual. Some toxins on the poison dart frog are 200 times stronger than morphine. Although toxins are deadly weapons against natural enemies, toxins have no effect on the poison dart frog itself.

The researchers performed genome sequencing and assembly analysis on the strawberry poison dart frog, and found that most of the genome of the strawberry poison dart frog is composed of highly repetitive sequences. Further comparative genomics studies have found that the repetitive elements of the strawberry poison dart frog have a large number of horizontal transfers between fish and frogs.

The genome size of the strawberry poison dart frog is 6.76–9 Gb, which is much larger than that of the quadruped. Studies have shown that the genome of these amphibians is so large that it can be explained to some extent that the changes in its genome are a process of continuous invasion of transposons, and these transposons have not been suppressed in the reproductive system.

The first poison frog genome was successfully analyzed, providing new ideas for studying the evolution of poison frogs.

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